Hey there, ladies and expecting moms! In the world of gynecology, few things are as crucial as keeping a pregnancy safe and sound, especially when preterm birth looms large. That's where Hydroxyprogesterone Injection IP 500 comes into play – a powerhouse medication that's saving countless babies from arriving too early. As part of Avosia Group's Femowin India, our gyne division is all about empowering women with top-notch solutions for reproductive health.
In this blog, we'll dive deep into what this injection is, why its so vital, and spotlight the leading manufacturers in India, with Femowin leading the charge. Stick around for insights, stats, and even some FAQs to clear up those nagging doubts. We've cranked up the details this time with real numbers, bullet points for quick reads, and tables to compare stuff – because who has time for walls of text, right?
Hydroxyprogesterone Injection IP 500(CPGEST HD-500) is essentially a synthetic version of the natural hormone progesterone, specifically the caproate form that's designed for intramuscular use. This 500mg dose is crafted to mimic what your body produces during pregnancy, helping to support the uterine lining and prevent contractions that could lead to early labor.
Its not just any hormone shot; its a targeted therapy approved for women at high risk of preterm delivery. In India, where preterm births affect around 13% of pregnancies – that's over 3 million cases yearly as per recent 2025 surveys – this injection is a beacon of hope. Femowin India's version ensures purity and efficacy, meeting IP standards that guarantee safety for every mom-to-be.
Think of it like a weekly guardian for your womb. Unlike everyday supplements, Hydroxyprogesterone Injection IP 500 delivers a steady release over days, keeping hormone levels balanced without the daily hassle. Its been a staple in obstetric care since the early 2000s, backed by trials showing it slashes preterm risks by up to 34% in high-risk cases. And get this, global market for these injections is booming, expected to grow at 6.2% CAGR through 2031, with India leading the charge thanks to rising awareness.
The primary use of Hydroxyprogesterone Injection IP 500 (CPGEST HD-500) is to reduce the risk of recurrent preterm birth in women carrying a single baby who've had one before. But its versatility doesn't stop there – doctors also prescribe it for luteal phase support in IVF cycles and even to manage certain endometrial issues. In a country like India, where maternal health challenges persist, this injection is tackling a silent epidemic. Did you know? Preterm births contribute to 75% of perinatal deaths here, and using Hydroxyprogesterone Injection IP 500 can prolong gestation by an average of 7 days, giving babies a fighting chance at healthier outcomes. Recent data from 2025 shows India's preterm rate holding at 13%, but interventions like this could drop it further if access improves.
For women's health, its a multitasker. By stabilizing the pregnancy, it cuts down on stress-related complications like gestational diabetes or hypertension, which plague 10-15% of Indian pregnancies. Moms who use it report feeling more confident, with fewer anxiety spikes about early delivery. Long-term? Healthier kids mean empowered families, and that's the ripple effect Femowin India aims for – healthier generations starting with better maternal care.
Studies confirm it lowers preterm birth risk by 34% in singleton pregnancies with history. Its not just about the baby; its about giving women the control and peace they deserve during this magical yet vulnerable time.
Using Hydroxyprogesterone Injection IP 500 is straightforward but must be doctor-supervised. The standard dose? One 500mg shot into the buttock muscle every seven days, kicking off between 16 and 20 weeks of pregnancy and wrapping up at 37 weeks – or earlier if delivery seems imminent. No self-administering here; a healthcare pro handles it to avoid mishaps like infections.
When to use it? If you've had a spontaneous preterm birth before, or if ultrasounds show a short cervix (less than 25mm), that's your cue. Doctors recommend it strongly for these scenarios, citing studies where it dropped preterm rates from 37% to 25%. Our Femowin experts always pair it with lifestyle tips: balanced diet, light exercise, and stress-busters like yoga, which is huge in Indian culture. In fact, with India's preterm numbers at 3.02 million in recent years, docs are pushing for earlier screenings.
Tablets sound convenient, right? But here's the kicker: oral progesterone gets broken down in the liver, losing potency – only 10-20% reaches your system. Injections bypass that, delivering 90%+ bioavailability for consistent levels that really work. Vaginal suppositories? Messy and less reliable for systemic effects.
Studies show injections prolong pregnancy better than orals, with 42% vs 63% preterm risk reduction. Plus, weekly dosing means fewer forget-me-nots, boosting compliance by 30% over daily pills. For busy Indian moms juggling work and home, its a no-brainer. Research even says IM injections like this one beat oral dydrogesterone in latency prolongation and neonatal scores.
Like any med, Hydroxyprogesterone Injection IP 500 has its quirks. Common side effects? Redness or pain at the injection site (affects 10-15% of users), mild nausea, diarrhea, or itchy hives. Rarer ones include blood sugar fluctuations or fluid retention – keep an eye if you're diabetic. Serious? Allergic reactions, but that's under 1%. Always chat with your doc if symptoms linger.
| Side Effect | Frequency | Management Tip |
|---|---|---|
| Injection site pain/swelling | Common (10-15%) | Apply ice, rotate sites |
| Nausea/Diarrhea | Common | Eat light meals, stay hydrated |
| Hives/Itching | Uncommon | Antihistamines if mild; see doc |
| Blood clots (rare) | Rare | Monitor for leg pain/swelling |
| Glucose changes | Uncommon in diabetics | Regular blood sugar checks |
Precautions in Bullets:
Suggestions? Hydrate well post-shot, monitor for swelling, and pair with folic acid for max benefits. Femowin India suggests regular check-ins to tweak as needed – personalized care is our mantra.
India's pharma market for progesterone therapies is on fire, with the Hydroxyprogesterone Caproate segment hitting USD 1444 million globally in 2025 and eyeing USD 2301 million by 2030. Locally, demand's up 15% yearly thanks to better rural access and govt pushes like PMMVY. Femowin India's riding this wave by expanding to distributors, making Hydroxyprogesterone Injection IP 500 available even in remote areas. Trends show a shift to generics, dropping prices 20% in two years, but quality's key – stick to GMP-certified like ours.
India's pharma scene is booming, and Hydroxyprogesterone Injection IP 500 production is no exception. Here's our curated list of the top 15, based on quality certifications, market share, and innovation. Remember, always go for IP-compliant ones for safety. We've added a quick comparison table below for easy scanning.
| Rank | Manufacturer | Brand Name | Price Range (INR) | Certifications |
|---|---|---|---|---|
| 1 | Femowin India (Avosia Group) | CPGEST HD-500 | 240 | WHO-GMP, ISO |
| 2 | Zydus Cadila | Proluton Depot | 250-300 | USFDA, GMP |
| 3 | Adorefem | Corpogest-Depot | 200-250 | GMP |
| 4 | Novalab Gynae Care | KASTGEST DEPOT | 190-230 | ISO |
| 5 | Farlex Pharmaceuticals | Gestokap-500 | 210-260 | GMP |
| 6 | Moruf Life Sciences | Moruf Gest | 170-210 | GMP |
| 7 | Macro Labs Pvt. Ltd. | MacroProgest | 220-270 | Export GMP |
| 8 | Acinom Healthcare | PG Health 500 | 180-220 | ISO |
| 9 | Indian Immunologicals Ltd | Progeshield | 240-290 | WHO-GMP |
| 10 | Steris Pharma | Hydroprogress 500 | 200-250 | GMP |
| 11 | Blister Healthcare | BlisterGest | 160-200 | ISO |
| 12 | Pharmavends | Prygestone 500 | 190-230 | GMP |
| 13 | Shree Sai Healthcare | SaiProgest | 150-190 | Local GMP |
| 14 | Aark Pharma | AarkGest | 210-260 | API GMP |
| 15 | Watran Pharmaceuticals | Hydowat-500 | 170-210 | ISO |
Femowin India tops the list because we don't just manufacture – we innovate for Indian women. Our Hydroxyprogesterone Injection IP 500 uses advanced lipid tech for less injection pain, and its priced 20% lower than competitors without skimping on quality. With WHO-GMP nods and zero recall history, its the doc's favorite. Plus, adding stabilizers for tropical climates – a real edge in humid India. In a market growing to USD 250 million by 2033, we're the affordable quality king.
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We're not just playing the game; we're rewriting it. By flooding rural pharmacies with affordable Hydroxyprogesterone Injection IP 500 or other Gyane products, we've boosted access by 40% in tier-2 cities. Looking ahead, our sustainable sourcing cuts carbon footprints, setting a green standard. Femowin is driving down preterm rates nationwide, one shot at a time, aligning with India's hormone therapy market hitting USD 1.48 billion by 2033.
A .It delivers sustained release for better efficacy in preventing preterm labor, unlike quick-fade orals. For top results, try Femowin India's version – its tailored for Indian bodies with minimal side effects.
Absolutely, especially if high-risk. Docs love it for older moms. Femowin India offers counseling to ease worries – our hotline's always open.
Within weeks, with reduced contractions. Pair it with Femowin India's prenatal kits for holistic support and track progress easily.
Yes, it boosts luteal support success rates. Femowin India's pure formula is a go-to for fertility clinics across India.
Get it ASAP, but don't double up. Femowin provides reminders via app – sign up for seamless tracking.
It is used to help prevent preterm birth in women with a history of premature delivery. For high-quality formulations, choose Femowin India.
Femowin India is one of the leading manufacturers offering WHO-GMP certified Hydroxyprogesterone injections with reliable quality and purity.
It supports the uterus during pregnancy by maintaining hormonal balance and reducing the risk of early labor. Always use products from approved sources like Femowin India.
It should be used only under medical supervision. Femowin India manufactures it under strict clinical and safety standards for assured quality.
It may help in some cases of recurrent pregnancy loss caused by progesterone deficiency. Consult your doctor and ensure the medicine is sourced from certified manufacturers like Femowin India.
It is primarily used to manage preterm labor, recurrent miscarriage, and hormonal imbalances during pregnancy. Femowin India provides this product for medical institutions across India.
It is given as an intramuscular injection by a qualified healthcare provider. Femowin India supplies vials with clear dosage and administration guidelines.
Ensure WHO-GMP, ISO, and Drug License certifications. Femowin India complies with all pharma quality norms and international standards.
Yes, Femowin India offers PCD pharma and monopoly distribution opportunities for this and other gynae range injections.
Mild pain or swelling at the injection site, nausea, or tiredness may occur. Always use genuine formulations like those by Femowin India.
Store below 25°C, protected from light and moisture. Follow manufacturer instructions — Femowin India provides detailed storage guidelines on packaging.
You can connect directly with Femowin India through their official website or sales team to request quotations, product samples, or franchise details.
In wrapping up, Hydroxyprogesterone Injection IP 500 isn't just a med; its a lifeline for millions of Indian women navigating pregnancy's uncertainties. With pioneers like Femowin India at the forefront, we're not only treating risks but transforming lives. If you're expecting or planning, chat with your gynae today – a simple shot could mean a fuller-term joy. Stay strong, stay healthy! Got questions? Drop 'em in comments.